About me
My name is Gufeng Yu from Yueyang, Hunan. I’m currently a Ph.D. candidate at the Department of Computer Science and Engineering, Shanghai Jiao Tong University, advised by Prof. Yang Yang. I obtained my Bachelor’s degree from School of Life Sciences and Biotechnology, Shanghai Jiao Tong University in 2023.
My research interest is AI for Science. Specifically, the main research areas are the application of AI in genomics and organic chemistry. Examples include gene regulatory network reconstruction, cancer genomics and chemical reaction prediction.
Recent News
- Mar. 2025, CLC-DB has been accepted by Journal of Cheminformatics!
- Dec. 2024, SubA has been accepted by Journal of Chemical Information and Modeling!
- Nov. 2023, MIGGRI has been accepted by PLOS Computational Biology!
Education
- Ph.D. in Computer Science and Technology, Shanghai Jiao Tong University, 2023-Now
- B.S. in Biotechnology (Bioinformatics), Shanghai Jiao Tong University, 2019-2023
Selected Publications
(#equal contribution, *corresponding)
- Clc-db: an open-source online database of chiral ligands and catalysts
Gufeng Yu#, Kaiwen Yu#, Xi Wang#, Chenxi Zhang, Yicong Luo, Xiaohong Huo*, Yang Yang*
Journal of Cheminformatics, 2025, 17(1): 1-12.
[Paper] - Machine Learning for Reaction Performance Prediction in Allylic Substitution Enhanced by Automatic Extraction of a Substrate-Aware Descriptor
Gufeng Yu#, Xi Wang#, Yicong Luo, Guanlin Li, Rui Ding, Runhan Shi, Xiaohong Huo*, Yang Yang*
Journal of Chemical Information and Modeling, 2025, 65(1): 312-325.
[Paper] - MIGGRI: A multi-instance graph neural network model for inferring gene regulatory networks for Drosophila from spatial expression images
Yuyang Huang#, Gufeng Yu#, Yang Yang*
PLOS Computational Biology, 2023, 19(11): e1011623.
[Paper]
Honors and Awards
Excellent Graduate | Shanghai Jiao Tong University (2023)
Gold Medal and Best Software Project Nomination | iGEM (2021)